Machine Learning-Based Early Breast Cancer Detection Through Temperature and Color Skin with Non-Invasive Smart Device
DOI:
https://doi.org/10.26555/jiteki.v10i4.30340Keywords:
Breast cancer detection, Physiological data, Non-invasive diagnostics, Machine Learning, Early screeningAbstract
Breast cancer remains a significant global health issue, affecting millions of women and often leading to late-stage diagnoses. Traditional diagnostic methods, such as mammograms, ultrasounds, and biopsies, are effective but can be costly, invasive, and not widely accessible, causing delays in detection and treatment. This research highlights the potential of using machine learning models with physiological data for early breast cancer detection. By capturing subtle physiological variations from a smart bra, the device allows real-time, non-invasive monitoring, offering a preventive solution that reduces the need for frequent clinical visits. The data were collected from a modified mannequin designed to simulate conditions related to breast cancer. To classify cancerous conditions based on temperature and color data, three machine learning models were evaluated. The Random Forest (RF) model proved to be the most effective, achieving 89% accuracy, 86.11% precision, 88.57% recall, and an F1-score of 87.33%, demonstrating strong performance in identifying complex patterns. The Support Vector Machine (SVM) achieved an accuracy of 81.25%, precision of 85.7%, recall of 80%, and an F1-score of 82.64%. The Multilayer Perceptron (MLP) exhibited an accuracy of 72%, precision of 69.69%, recall of 65.71%, and an F1-score of 67.52%, suggesting potential but requiring further optimization. These models serve as valuable tools to assist medical professionals in early screening efforts. Future research should aim to improve the models’ generalizability by expanding the dataset, utilizing data augmentation, applying transfer learning, and incorporating additional variables. Clinical validation and human trials are essential next steps to evaluate the system's effectiveness.
References
[1] R. Wang, Y. Zhu, X. Liu, X. Liao, J. He, and L. Niu, “The Clinicopathological features and survival outcomes of patients with different metastatic sites in stage IV breast cancer,” BMC Cancer, vol. 19, no. 1, pp. 1–12, 2019, https://doi.org/10.1186/s12885-019-6311-z.
[2] Y. Xu, M. Gong, Y. Wang, Y. Yang, S. Liu, and Q. Zeng, “Global trends and forecasts of breast cancer incidence and deaths,” Sci. Data, vol. 10, no. 1, pp. 1–10, 2023, https://doi.org/10.1038/s41597-023-02253-5.
[3] M. Karbakhsh, “Global Breast Cancer Initiative: an Integrative Approach to Thinking Globally, Acting Locally,” Arch. Breast Cancer, vol. 8, no. 2, pp. 63–64, 2021, https://doi.org/10.32768/abc.20218263-64.
[4] G. P. Cristy, D. Liana, J. Chatwichien, C. Aonbangkhen, C. Srisomsap, and A. Phanumartwiwath, “Breast Cancer Prevention by Dietary Polyphenols: Microemulsion Formulation and In Vitro Studies,” Sci. Pharm., vol. 92, no. 2, 2024, https://doi.org/10.3390/scipharm92020025.
[5] H. Sung et al., “Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries,” CA. Cancer J. Clin., vol. 71, no. 3, pp. 209–249, 2021, https://doi.org/10.3322/caac.21660.
[6] H. C. W. Choi, K. O. Lam, H. H. M. Pang, S. K. C. Tsang, R. K. C. Ngan, and A. W. M. Lee, “Global comparison of cancer outcomes: Standardization and correlation with healthcare expenditures,” BMC Public Health, vol. 19, no. 1, pp. 1–11, 2019, https://doi.org/10.1186/s12889-019-7384-y.
[7] M. Arnold et al., “Current and future burden of breast cancer: Global statistics for 2020 and 2040,” Breast, vol. 66, pp. 15–23, 2022, https://doi.org/10.1016/j.breast.2022.08.010.
[8] J. Ahmad, S. Akram, A. Jaffar, M. Rashid, and S. M. Bhatti, “Breast Cancer Detection Using Deep Learning: An Investigation Using the DDSM Dataset and a Customized AlexNet and Support Vector Machine,” IEEE Access, vol. 11, pp. 108386–108397, 2023, https://doi.org/10.1109/ACCESS.2023.3311892.
[9] M. A. Aldhaeebi, K. Alzoubi, T. S. Almoneef, S. M. Bamatra, H. Attia, and O. M. Ramahi, “Review of microwaves techniques for breast cancer detection,” Sensors (Switzerland), vol. 20, no. 8, pp. 1–38, 2020, https://doi.org/ 10.3390/s20082390.
[10] A. Mashekova, Y. Zhao, E. Y. K. Ng, V. Zarikas, S. C. Fok, and O. Mukhmetov, “Early detection of the breast cancer using infrared technology – A comprehensive review,” Therm. Sci. Eng. Prog., vol. 27, p. 101142, 2022, https://doi.org/10.1016/j.tsep.2021.101142.
[11] Y. Ming et al., “Progress and Future Trends in PET/CT and PET/MRI Molecular Imaging Approaches for Breast Cancer,” Front. Oncol., vol. 10, pp. 1–13, 2020, https://doi.org/10.3389/fonc.2020.01301.
[12] R. M. Mann, N. Cho, and L. Moy, “Breast MRI: State of the art,” Radiology, vol. 292, no. 3, pp. 520–536, 2019, https://doi.org/10.1148/radiol.2019182947.
[13] J. Zhang, B. Chen, M. Zhou, H. Lan, and F. Gao, “Photoacoustic Image Classification and Segmentation of Breast Cancer: A Feasibility Study,” IEEE Access, vol. 7, pp. 5457–5466, 2019, https://doi.org/10.1109/ACCESS.2018.2888910.
[14] S. Iranmakani et al., “A review of various modalities in breast imaging: technical aspects and clinical outcomes,” Egypt. J. Radiol. Nucl. Med., vol. 51, no. 1, 2020, https://doi.org/10.1186/s43055-020-00175-5.
[15] T. Mortezazadeh, E. Gholibegloo, A. N. Riyahi, S. Haghgoo, A. E. Musa, and M. Khoobi, “Glucosamine conjugated gadolinium (III) oxide nanoparticles as a novel targeted contrast agent for cancer diagnosis in MRI,” J. Biomed. Phys. Eng., vol. 10, no. 1, pp. 25–38, 2020, https://doi.org/10.31661/jbpe.v0i0.1018.
[16] J. Zhao et al., “Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019,” BMJ Oncol., vol. 2, no. 1, pp. 1–12, 2023, https://doi.org/10.1136/bmjonc-2023-000049.
[17] M. B. Rakhunde, S. Gotarkar, and S. G. Choudhari, “Thermography as a Breast Cancer Screening Technique: A Review Article,” Cureus, vol. 14, no. 11, 2022, https://doi.org/10.7759/cureus.31251.
[18] C. H. Barrios, “Global challenges in breast cancer detection and treatment,” Breast, vol. 62, no. S1, pp. S3–S6, 2022, https://doi.org/10.1016/j.breast.2022.02.003.
[19] G. Masawa and J. F. Mboineki, “Assessing breast self-examination knowledge, attitude and practice as a secondary prevention of breast cancer among female undergraduates at the University of Dodoma: a protocol of analytical cross-sectional study,” Front. Epidemiol., vol. 4, pp. 1–6, 2024, https://doi.org/10.3389/fepid.2024.1227856.
[20] A. V. Icanervilia et al., “A Qualitative Study: Early Detection of Breast Cancer in Indonesia (After Universal Health Coverage Implementation),” pp. 1–14, 2021, [Online]. Available: https://www.researchsquare.com/article/rs-936413/latest%0Ahttps://www.researchsquare.com/article/rs-936413/latest.pdf.
[21] Y. Azhar, R. V. Hanafi, B. W. Lestari, and F. S. Halim, “Breast Self-Examination Practice and Its Determinants among Women in Indonesia: A Systematic Review, Meta-Analysis, and Meta-Regression,” Diagnostics, vol. 13, no. 15, 2023, https://doi.org/10.3390/diagnostics13152577.
[22] T. T. Ngan, S. Browne, M. Goodwin, H. Van Minh, M. Donnelly, and C. O’Neill, “Cost-effectiveness of clinical breast examination screening programme among HER2-positive breast cancer patients: a modelling study,” Breast Cancer, vol. 30, no. 1, pp. 68–76, 2023, https://doi.org/10.1007/s12282-022-01398-2.
[23] H. E. Saroğlu et al., “Machine learning, IoT and 5G technologies for breast cancer studies: A review,” Alexandria Eng. J., vol. 89, pp. 210–223, 2024, https://doi.org/10.1016/j.aej.2024.01.043.
[24] H. Liu et al., “Artificial Intelligence-Based Breast Cancer Diagnosis Using Ultrasound Images and Grid-Based Deep Feature Generator,” Int. J. Gen. Med., vol. 15, pp. 2271–2282, 2022, https://doi.org/10.2147/IJGM.S347491.
[25] L. Wang, “Mammography with deep learning for breast cancer detection,” Front. Oncol., vol. 14, no. February, pp. 1–16, 2024, https://doi.org/10.3389/fonc.2024.1281922.
[26] A. Carriero, L. Groenhoff, E. Vologina, P. Basile, and M. Albera, “Deep Learning in Breast Cancer Imaging: State of the Art and Recent Advancements in Early 2024,” Diagnostics, vol. 14, no. 8, 2024, https://doi.org/10.3390/diagnostics14080848.
[27] Y. Shen et al., “Artificial intelligence system reduces false-positive findings in the interpretation of breast ultrasound exams,” Nat. Commun., vol. 12, no. 1, 2021, https://doi.org/10.1038/s41467-021-26023-2.
[28] A. Khamparia et al., “Diagnosis of breast cancer based on modern mammography using hybrid transfer learning,” Multidimens. Syst. Signal Process., no. 0123456789, 2021, https://doi.org/10.1007/s11045-020-00756-7.
[29] A. Alshehri and D. AlSaeed, “Breast Cancer Diagnosis in Thermography Using Pre-Trained VGG16 with Deep Attention Mechanisms,” Symmetry (Basel)., vol. 15, no. 3, 2023, https://doi.org/10.3390/sym15030582.
[30] N. Aidossov et al., “An Integrated Intelligent System for Breast Cancer Detection at Early Stages Using IR Images and Machine Learning Methods with Explainability,” SN Comput. Sci., vol. 4, no. 2, pp. 1–16, 2023, https://doi.org/10.1007/s42979-022-01536-9.
[31] R. F. Fruntelată et al., “Assessment of tumoral and peritumoral inflammatory reaction in cutaneous malignant melanomas,” Rom. J. Morphol. Embryol., vol. 64, no. 1, pp. 41–48, 2023, https://doi.org/10.47162/RJME.64.1.05.
[32] C. E. Wells and R. Killingsworth, “Better than the human eye – machine learning models to objectively analyze bovine embryo quality,” Am. Assoc. Bov. Pract. Conf. Proc., vol. 55, no. 55, p. 214, 2023, https://doi.org/10.21423/aabppro20228687.
[33] A. Lozano, J. C. Hayes, L. M. Compton, J. Azarnoosh, and F. Hassanipour, “Determining the thermal characteristics of breast cancer based on high-resolution infrared imaging, 3D breast scans, and magnetic resonance imaging,” Sci. Rep., vol. 10, no. 1, pp. 1–14, 2020, https://doi.org/10.1038/s41598-020-66926-6.
[34] A. Shimatani, M. Hoshi, N. Oebisu, N. Takada, Y. Ban, and H. Nakamura, “An analysis of tumor-related skin temperature differences in malignant soft-tissue tumors,” Int. J. Clin. Oncol., vol. 27, no. 1, pp. 234–243, 2022, https://doi.org/10.1007/s10147-021-02044-1.
[35] M. Neagu, C. Constantin, C. Caruntu, C. Dumitru, M. Surcel, and S. Zurac, “Inflammation: A key process in skin tumorigenesis (Review),” Oncol. Lett., vol. 17, no. 5, pp. 4068–4084, 2019, https://doi.org/10.3892/ol.2018.9735.
[36] C. Y. Guo and Y. J. Lin, “Random Interaction Forest (RIF)-A Novel Machine Learning Strategy Accounting for Feature Interaction,” IEEE Access, vol. 11, pp. 1806–1813, 2023, https://doi.org/10.1109/ACCESS.2022.3233194.
[37] N. Elsayed, S. A. Elaleem, and M. Marie, “Improving Prediction Accuracy using Random Forest Algorithm,” Int. J. Adv. Comput. Sci. Appl., vol. 15, no. 4, pp. 436–441, 2024, https://doi.org/10.14569/IJACSA.2024.0150445.
[38] V. Distefano, M. Palma, and S. De Iaco, “Multi-class random forest model to classify wastewater treatment imbalanced data,” Socioecon. Plann. Sci., vol. 95, no. July, p. 102021, 2024, https://doi.org/10.1016/j.seps.2024.102021.
[39] T. S. Lim, K. G. Tay, A. Huong, and X. Y. Lim, “Breast cancer diagnosis system using hybrid support vector machine-artificial neural network,” Int. J. Electr. Comput. Eng., vol. 11, no. 4, pp. 3059–3069, 2021, https://doi.org/ 10.11591/ijece.v11i4.pp3059-3069.
[40] E. Akkur, F. TURK, and O. Erogul, “Breast Cancer Diagnosis Using Feature Selection Approaches and Bayesian Optimization,” Comput. Syst. Sci. Eng., vol. 45, no. 2, pp. 1017–1031, 2023, https://doi.org/10.32604/csse.2023.033003.
[41] N. Fatima, L. Liu, S. Hong, and H. Ahmed, “Prediction of Breast Cancer, Comparative Review of Machine Learning Techniques, and Their Analysis,” IEEE Access, vol. 8, pp. 150360–150376, 2020, https://doi.org/10.1109/ACCESS.2020.3016715.
[42] L. C. Camargo, H. C. Tissot, and A. T. R. Pozo, “Use of backpropagation and differential evolution algorithms to training MLPs,” Proc. - Int. Conf. Chil. Comput. Sci. Soc. SCCC, pp. 78–86, 2012, https://doi.org/10.1109/SCCC.2012.17.
[43] M. Desai and M. Shah, “An anatomization on breast cancer detection and diagnosis employing multi-layer perceptron neural network (MLP) and Convolutional neural network (CNN),” Clin. eHealth, vol. 4, no. 2021, pp. 1–11, 2021, https://doi.org/10.1016/j.ceh.2020.11.002.
[44] M. Ghorbian and S. Ghorbian, “Usefulness of machine learning and deep learning approaches in screening and early detection of breast cancer,” Heliyon, vol. 9, no. 12, p. e22427, 2023, https://doi.org/10.1016/j.heliyon.2023.e22427.
[45] M. Owusu-Adjei, J. Ben Hayfron-Acquah, T. Frimpong, and G. Abdul-Salaam, “Imbalanced class distribution and performance evaluation metrics: A systematic review of prediction accuracy for determining model performance in healthcare systems,” PLOS Digit. Heal., vol. 2, no. 11, pp. 1–23, 2023, https://doi.org/10.1371/journal.pdig.0000290.
[46] S. Khan, H. U. Khan, and S. Nazir, “Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing,” Sci. Rep., vol. 12, no. 1, pp. 1–21, 2022, https://doi.org/10.1038/s41598-022-26090-5.
[47] F. Rahmad, Y. Suryanto, and K. Ramli, “Performance Comparison of Anti-Spam Technology Using Confusion Matrix Classification,” IOP Conf. Ser. Mater. Sci. Eng., vol. 879, no. 1, 2020, https://doi.org/10.1088/1757-899X/879/1/012076.
[48] A. Y. Mahmoud, D. Neagu, D. Scrimieri, and A. R. A. Abdullatif, “Early diagnosis and personalised treatment focusing on synthetic data modelling: Novel visual learning approach in healthcare,” Comput. Biol. Med., vol. 164, 2023, https://doi.org/10.1016/j.compbiomed.2023.107295.
[49] Z. DeVries et al., “Using a national surgical database to predict complications following posterior lumbar surgery and comparing the area under the curve and F1-score for the assessment of prognostic capability,” Spine J., vol. 21, no. 7, pp. 1135–1142, 2021, https://doi.org/10.1016/j.spinee.2021.02.007.
[50] D. Theodorakopoulos, F. Stahl, and M. Lindauer, “Hyperparameter Importance Analysis for Multi-Objective AutoML,” arXiv preprint arXiv:2405.07640, 2024, [Online]. Available: http://arxiv.org/abs/2405.07640.
[51] M. Anisetti, C. A. Ardagna, A. Balestrucci, N. Bena, E. Damiani, and C. Y. Yeun, “On the Robustness of Random Forest Against Untargeted Data Poisoning: An Ensemble-Based Approach,” IEEE Trans. Sustain. Comput., vol. 8, no. 4, pp. 540–554, 2023, https://doi.org/10.1109/TSUSC.2023.3293269.
[52] T. K. Choudhury, “Enhancing Diagnostic: Machine Learning in Medical Image Analysis,” Interantional J. Sci. Res. Eng. Manag., vol. 08, no. 05, pp. 1–5, 2024, https://doi.org/10.55041/ijsrem35273.
[53] H. Zhu, P. Zhao, Y. P. Chan, H. Kang, and D. L. Lee, “Breast Cancer Early Detection with Time Series Classification,” Int. Conf. Inf. Knowl. Manag. Proc., pp. 3735–3745, 2022, https://doi.org/10.1145/3511808.3557107.
[54] A. Elouerghi, L. Bellarbi, Z. Khomsi, A. Jbari, A. Errachid, and N. Yaakoubi, “A Flexible Wearable Thermography System Based on Bioheat Microsensors Network for Early Breast Cancer Detection: IoT Technology,” J. Electr. Comput. Eng., vol. 2022, 2022, https://doi.org/10.1155/2022/5921691.
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