FORMULASI VANISHING CREAM MINYAK ATSIRI RIMPANG JAHE (Zingiber officinale Roxb) DAN UJI AKTIVITAS REPELAN TERHADAP NYAMUK Aedes aegypti BETINA

Abstract

The essential oil of Ginger rhizome is a natural subtance which has been proved
to have a repellent effect to the mosquito. The aim of this study was to know the effect of
this subtance/these substances in vanishing cream dosage forms as repellant to the
female Aedes aegypti mosquito. The essential oil of Ginger rhizome was isolated with
aqueous vapor destillation. Then the result was determined for its physical properties,
these were: viscosity, adhesivity, spreadibility and its repellant effect to mosquito as
well. The vanishing cream formulation, containing variation of the essential oil
concentration were prepared, these were: FI (formulation I), FII, FIII, FIV and FV,
containing 6,25%, 12,5%, 15%, 20% and 25% of the essential oil respectivity. Each
formulas were tested for their physical properties were viscosity, adhesivity,
spreadibility and its repellant effect to mosquito as well. The datas were analyzed.
Statistically using SPSS version 16 with Kolmogorov-Smirnov and continued with the
t-test (Mann-Whitney) (=0,05). The result showed that the duration of the adhesivity
of FI was the longest than the others (1,37±0,15 minutes); the spreadibility of the FI
was widest (71,69±1,76 mm2
), and the viscosity was the largert than others (27±0 cps).
The repellant capasity of the FV was the longest than the others (47,3±1,80 minutes).