OPTIMASI KOMPOSISI TEPUNG BERAS DAN FRAKSI ETANOL DAUN SENDOK (Plantago major, L) DALAM FORMULASI TABIR SURYA DENGAN METODE SIMPLEX LATTICE DESIGN

Authors

  • Nining Sugihartini Fakultas Farmasi UAD

DOI:

https://doi.org/10.12928/pharmaciana.v1i2.525

Keywords:

Octyl methoxycinamate, rice flour, fraction of leaf ethanol extract Plantago major, L., Sunscreen

Abstract

Octyl methoxycinnamate is an active ingredient in sunscreen that will be
degradated after exposure by sunlight. On the other hand, antioxidants have potential
capability as photoprotector which in this study is used the ethanol fraction of leaf of
Plantago major, L to support activity of OMS. In addition, rice flour is added too
because it has the ability to reflect sunlight. The aim of this study is to obtain the
optimum composition of them, based on the effectivity of OMS. This study used three
formulas based on the simplex lattice design method with a comparison of octyl
methoxycinnamate and rice flour as follows: FI (100%: 0%), the formula II (50%:
50%), formula III (0%: 100%). All formulas were exposured by sunlight for 5 hours (at
09:00 to 14:00 GMT) and in interval one hour samples were taken to measure the value
of % erythema transmission (% Te) and pigmentation (% Tp). Data were analysed to
get the optimum composition which has the highest of response. The results showed that
100% rice flour was the optimum addition to support activity of OMS as sunscreen with
decreasing of % erythema transmission and pigmentation was 200%, 75%,
respectively.

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Published

2011-11-01

Issue

Vol. 1 No. 2 (2011): Pharmaciana

Section

Analytical Pharmacy and Medicinal Chemistry

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