PENGEMBANGAN SENYAWA TURUNAN BENZALASETON SEBAGAI SENYAWA TABIR SURYA

Authors

  • Susy Yunita Prabawati Prodi Kimia, Fakultas Sains dan Teknologi UIN yogyakarta
  • A Wijayanto Laboratorium Kimia, Fakultas Sains dan Teknologi UIN yogyakarta
  • Aria Wirahadi Prodi Kimia, Fakultas Sains dan Teknologi UIN yogyakarta

DOI:

https://doi.org/10.12928/pharmaciana.v4i1.395

Keywords:

benzalaceton, sunscreen, ultra protection

Abstract

The goal of this research was to synthesize benzalaceton derivative i.e. 4-dimethyl-aminodibenzalaceton
to increase the potency as sunscreen agent. The synthesis was carried out through aldol
condensation reaction with 4- dimetilamino-benzaldehida as a starting material and NaOH as catalyst
at various reaction times i.e. 3 , 4 and 6 hours. The characterizations of the product was observed by
melting point, FTIR and 1
H NMR spectrometers. The product was obtained as a yellowish orange
solid with a melting point between 62-640
C. The activity assay as sunscreen agent showed that the 4 –
dimethylamino-dibenzalaseton have a maximum wavelength at 340 nm, so its can be active as a
sunscreen in the UV - A rays. The SPF value at 15 ppm was 17.409 with ultra protection type.

Downloads

Published

2014-05-01

Issue

Vol. 4 No. 1 (2014): Pharmaciana

Section

Analytical Pharmacy and Medicinal Chemistry

License

Authors who publish with Pharmaciana agree to the following terms:

  1. Authors retain copyright and grant the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. 
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.