Phytochemical and antibacterial analyses of essential oils extracted from the leaves of Euodia suaveolens scheff

Authors

  • Boy Rahardjo Sidharta Biology Study Program Faculty of Biotechnology Universitas Atma Jaya Yogyakarta http://orcid.org/0000-0002-6038-6588
  • Patricius Kianto Atmodjo Biotechno-Industry Research Group Faculty of Biotechnology Universitas Atma Jaya Yogyakarta

DOI:

https://doi.org/10.12928/pharmaciana.v14i2.25827

Keywords:

antibacterial activity, essential oil, Euodia suaveolens

Abstract

Euodia suaveolens is one of the plants that ancient people in Indonesia used due to its manifold benefits. Earlier research on this plant was mostly done on its potency as a mosquito repellent. This present study aims to determine the phytochemical and antibacterial analyses of the essential oils (EOs) extracted from the leaves of E. suaveolens. The EOs of the leaves of E. suaveolens were extracted by steam distillation method and were analyzed phytochemically utilizing the GC-MS technique to determine the chemical constituents. The chemical components were tested on four pathogenic bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis utilizing the diffusion agar method. The results showed that the main compounds extracted from the EOs were delta curcumene, evodone, globulol, limonene, linalool, longipinenepoxide, menthofuran, and p-mentha-1,8-diene. The antibacterial analysis of these compounds showed potential activities to inhibit the growth of four pathogenic bacteria tested, but the inhibition zones formed were still lower compared to commercial antibiotic kanamycin. E. suaveolens EOs exhibited diameter of zone of inhibition as follows 2.03 plus minus 0.22, 0.50 plus minus 0.49, 1.38 plus minus 0.10, 1.40 plus minus 0.27 cm to E. coli, P. aeruginosa, S. aureus, and S. epidermidis while kanamycin showed 3.43 plus minus 0.08, 3.25 plus minus 0.08, 3.38 plus minus 0.12, and 3.18 plus minus 0.24 cm respectively. These results recommend that the main compounds extracted from the EOs of the leaves of E. suaveolens be explored further to determine their potencies as new antibiotic medications.

 

Author Biography

Boy Rahardjo Sidharta, Biology Study Program Faculty of Biotechnology Universitas Atma Jaya Yogyakarta

Senior Lecturer and Researcher

Bio-Industry Laboratory

Biology Study Program

Faculty of Biotechnology

Universitas Atma Jaya Yogyakarta

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Published

2024-07-23

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Section

Biology Pharmacy