PERBANDINGAN AKTIVITAS REPELAN ANTARA KRIM MINYAK ATSIRI JAHE (Zingiber offinale, Roxb) DENGAN KRIM MINYAK ATSIRI SERE (Cymbopogon citratus (D.C) Stapf) TERHADAP NYAMUK Aedes aegypti BETINA

Authors

  • Azis Ikhsanudin

DOI:

https://doi.org/10.12928/pharmaciana.v4i2.1568

Keywords:

sere, ginger, essential oils, repellent, Aedes aegypti

Abstract

The one efforts to prevent dengue fever is to prevent mosquito bites by using mosquito
repellent preparations. The nature of the toxicity of synthetic repellent be the reason for the
research came from the plant. Sere and ginger into one of mosquito repellent plant because it
contains of natural essential oils are many. The aim of this study was to determine the comparative
ability repelan effects of essential oils cream sere (Cymbopogon citratus (DC) Stapf) and ginger
(Zingiber officinale Roxb). The essential oil of sere (Cymbopogon citratus (DC) Stapf and ginger
(Zingiber officinale Roxb), obtained by isolation of leaves and rhizome by steam distillation of
water which is then tested physical properties including test of adhesion, test of spreadability and
test of mosquito repellent activities. The test of mosquito repellent activities using 20 birds Aedes
aegypti mosquito female per cage with the using hand of women as volunteers as much as 4
people. In this study were divided into sixth formulas of test. The sixth of cream formula with
variations in the concentration of essential oils sere and ginger wherein the formula I, II and III
contain essential oils sere as much as 20% v/w; 30% v/ w and 40% v/w, whereas for formula IV; V;
and VI contain the essential oil of ginger as much as 6.25% v/w; 12.5% v/w and 25% v/w. Data of
physical properties test were analyzed statistically using SPSS. The results showed the cream with
the concentration of essential oils sere 40% v/w (FIII) have better outcomes than others formulas
cream, where than of adhesion test is 0.46 ± 0.04 seconds; of the spreadibility test is 56.32 ± 14.78
cm2 and repellent effect of 3014.2 ± 20.16 seconds.

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Published

2014-11-01

Issue

Vol. 4 No. 2 (2014): Pharmaciana

Section

Analytical Pharmacy and Medicinal Chemistry

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