The development of antioxidant peel-off facial masks from cinnamon bark extract (Cinnamomum burmannii)

Authors

  • Sani Ega Priani Pharmacy Department, Bandung Islamic University
  • Restianti Mutiara Pharmacy Department, Bandung Islamic University
  • Dina Mulyanti Pharmacy Department, Bandung Islamic University

DOI:

https://doi.org/10.12928/pharmaciana.v10i1.14193

Keywords:

peel-off mask, cinnamon bark, ethanol extract, antioxidant

Abstract

The bark of cinnamon (Cinnamomum burmannii) contains cinnamaldehyde and other active substances with potent antioxidant properties. Antioxidants are effective at preventing and reducing UV-induced skin damages and skin aging. This study was intended to formulate and characterize the antioxidant peel-off facial masks containing cinnamon bark extract and the combination of polyvinyl alcohol (PVA) and hydroxypropyl methylcellulose (HPMC) as gelling agents. The ethanol extract of cinnamon bark and the developed peel-off mask were evaluated for their antioxidant activities by the α,α-diphenyl-β-picrylhydrazyl (DPPH) free radical scavenging method and for their physical characteristics. The cinnamon bark extract exhibited a very strong antioxidant activity, as evidenced by IC50= 10.04 ± 0.08 ppm. As for the formulated peel-off mask, it had excellent physical characteristics, which were identified during organoleptic observations and pH, viscosity, spreadability, and film drying time evaluations. Similar to its constituent extract, this mask produced significantly potent antioxidant effects, with IC50= 47.31 ± 1.47 ppm. For these reasons, peel-off facial masks containing cinnamon bark extract have not only excellent physical characteristics but also powerful antioxidant properties.

References

Al-Dhubiad, B.E., 2012, Pharmaceutical Applications and Phytochemical Profile of Cinnamomum burmannii, Article Pharmacognosy Review, 6 (12): 125-131.

Berighs, A.O., Julia, M.R., Hellen, K.S., 2013, Green clay and aloe vera peel-off facial masks: response surface methodology applied to the formulation design, AAPS Pharm Sci Tech, 4(1): 445-455.

Fransworth, N.R., 1966, Biological and Phytochemical Screening of Plants, Journal of Pharmaceutical Sciences, 55(3): 225-240

Garg, A., Aggarwal, D., Garg, S., Singla, A.K., 2002, Spreading of semisolid formulations A update, Pharmaceutical Technology North America, 26(9):84 â€105.

Godic, A., Borut, P., Metka, A., 2014, The Role of Antioxidants in Skin Cancer Prevention and Treatment, Oxidative Medicine and Cellular Longevity, 2014: 1-7.

Haque, T., Talukder, M.M.U., 2018, Chemical Enhancer: A Simplistic Way to Modulate Barrier Function of the Stratum Corneum, Advanced Pharmaceutical Bulletin, 8(2):169-179.

Hanum, I.T., Lia, L., 2016, Physical Evaluation of Anti-aging and Anti-acne Andaliman (Zanthoxylum acanthopodium DC.) Ethanolic Extract Peel Off Gel Mask, Der Pharma Chemica, 8(23):6-10.

Molyneux, P., 2004, The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity, Journal of Science and Technology, 6(2): 211-219.

More, B.H., Sakharwade, S.N., Tembhurne, S.V., 2013, Evaluation for irritancy testing of developed formulations containing extract of Butea monosperma for its topical application, Int Journal of Toxicology and Applied Pharmacology, 3(1): 10-13.

Pandel, R., Borut, P., Aleksandar, G., Raja, D., 2013, Skin Photoaging and the Role of Antioxidants in Its Prevention, ISRN Dermatolog, 2013: 1-11.

Priani, S.E., Fitrianti, D., Haniva, H., 2014, Formulasi Sediaan Emulgel Antioksidan Mengandung Ekstrak Etanol Kulit Buah Manggis, Prosiding SNAPPS, 4(1): 103-110.

Priani, S.E., Fitrianti, D., Haniva, H., 2014, Development of sunscreen emulgel containing Cinnamomum burmannii stem bark extract, International Journal of Science and Research, 3(13): 2338-2339.

Priani, S.E., Irma, I., Fitrianti, D., 2015, Formulasi Masker Gel Peel-Off Kulit Buah Manggis (Garcinia mangostana Linn.), Indonesian Journal of Pharmaceutical Science and Technology, 2(3): 90-95.

Rao, P.V., Siew, H.G., 2014, Cinnamon: A Multifaceted Medicinal Plant, Evidence Based Complement Alternative Medicine, 2014: 1-12.

SÃ, A., Rosso, Sibele, Ferreira, Sandra, 2015, Antioxidant Activity and Chemical Composition of Supercritical and conventional extract of cinnamon, Conference: xx Congresso Brasileiro de Engenharia Química: 1-8.

Setha, B., Febe, F.G., Andi, P.S., Idris, Samsul, R., Meigy, N.M., 2013, Potential of seaweed Padina sp. as a source of antioxidant, International of Scientific and Technology Research, 2(6): 2013, 221-224.

Suhery, W.N., Nia, A., 2016, Formulation and Evaluation of Peel-off Gel Masks from Red Rice Bran Extract with Various Kind of Bases, International Journal of PharmTech Research, 9(12): 574-580.

Singh, G., Maurya, S., DeLampasona, M.P., Catalan, C.A., 2007, A comparison of chemical, antioxidant and antimicrobial studies of cinnamon leaf and bark volatile oils, oleoresins and their constituents, Food Chemical Toxicology, 45(9): 1650-1661.

Vieira, R.P., Alessandra R.F., Telma, M.K., Vladi, O.C., 2009, Physical and physicochemical stability evaluation of cosmetic formulations containing soybean extract fermented by bifidobacterium animalis, Brazilian Journal of Pharmaceutical Sciences, 45(3): 515-525.

Vishnuvardhanaraj, G., Tamilvendan, D., Amaladasant, M., 2013, Synthesis, characterization, and biologycal activities of cinnamaldehydes mannich base International Journal of Pharmacy and Pharmaceutical Sciences, 5(3): 821-825.

Wendtner, M.H., Korting, H.C., 2006, The pH of the skin surface and its impact on the barrier function, Skin Pharmacol Physiol, 19(6): 296-301.

Downloads

Published

2020-03-24

Issue

Section

Pharmaceutics and Pharmaceutical Technology