Type the Prescription patterns in the Outpatient Unit of XYZ Hospital, Pekanbaru: A Study from 2022
Keywords:
Hospital Prescribing, Quality of Heal Service, Healthcare ServiceAbstract
This study aims to assess the rationality of drug prescribing practices in the Outpatient Department of XYZ Hospital Pekanbaru using the World Health Organization (WHO) prescribing indicators. The research is an observational study with a descriptive nature, employing systematic random sampling to analyze data extracted from prescription records in the pharmacy department of XYZ Hospital Pekanbaru. A total of 660 prescription samples were evaluated, revealing an average of 2.91 drugs prescribed per prescription sheet, indicating a lack of adherence to diagnostic considerations. The findings show that the percentage of generic drug prescriptions was 64.04%, while antibiotic prescriptions accounted for 32.57%. Additionally, prescriptions for injectable forms constituted 1.36%, and adherence to the national formulary was at 72.27%. Out of the five prescribing indicators assessed, only the prescribing of injectable forms met the WHO’s prescribing indicators standard. These results highlight the necessity for improved adherence to rational prescribing practices to enhance treatment efficacy, minimize adverse drug reactions, and ensure cost-effectiveness in patient care. Regular monitoring and education of healthcare providers regarding rational drug use principles are essential for improving healthcare service quality.
References
Abed, V., Lemaster, N. G., Hawk, G. S., Thompson, K. L., Conley, C. E. W., Mair, S. D., & Jacobs, C. A. (2023). Patients With Depression and/or Anxiety Having Arthroscopic Rotator Cuff Repair Show Decreased Number of Prescriptions and Number of Psychotherapy Sessions in the Year After Surgery. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 39(12), 2438-2442.e2439. https://doi.org/https://doi.org/10.1016/j.arthro.2023.05.032
Andayani, T. M., & Satibi, S. (2016). Chapter 3 - Pharmacy Practice in Indonesia. In A. I. Fathelrahman, M. I. M. Ibrahim, & A. I. Wertheimer (Eds.), Pharmacy Practice in Developing Countries (pp. 41-56). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-12-801714-2.00003-4
Andrajati, R., Tilaqza, A., & Supardi, S. (2017). Factors related to rational antibiotic prescriptions in community health centers in Depok City, Indonesia. Journal of Infection and Public Health, 10(1), 41-48. https://doi.org/https://doi.org/10.1016/j.jiph.2016.01.012
Anggriani, Y., Ramadaniati, H. U., Sarnianto, P., Pontoan, J., & Suryawati, S. (2020). The Impact of Pharmaceutical Policies on Medicine Procurement Pricing in Indonesia Under the Implementation of Indonesia’s Social Health Insurance System. Value in Health Regional Issues, 21, 1-8. https://doi.org/https://doi.org/10.1016/j.vhri.2019.05.005
Aparasu, R. R., & Rege, S. (2022). Chapter 36 - Use of national databases and surveys to evaluate prescribing patterns and medication use. In S. P. Desselle, V. García-Cárdenas, C. Anderson, P. Aslani, A. M. H. Chen, & T. F. Chen (Eds.), Contemporary Research Methods in Pharmacy and Health Services (pp. 527-539). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-323-91888-6.00029-6
Atmaja, D. S., Saksono, R. Y., Yulistiani, Suharjono, & Zairina, E. (2024). Evaluation of medication errors in one of the largest public hospital: A retrospective study. Clinical Epidemiology and Global Health, 28, 101640. https://doi.org/https://doi.org/10.1016/j.cegh.2024.101640
Baskoro, A., Situmorang, G. R., & Widia, F. (2024). Pattern of enuresis diagnosis and management by general practitioner in Indonesia. Continence, 12, 101701. https://doi.org/https://doi.org/10.1016/j.cont.2024.101701
Elbeddini, A., Yeats, A., & Gazarin, M. (2023). Chapter 3 - Deprescribing is an essential part of prescribing. In A. Elbeddini (Ed.), Deprescribing and Polypharmacy in an Aging Population (pp. 49-67). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-323-99138-4.00003-5
Eltayeb, A., & Leaver, S. (2024). Bacterial infections of the respiratory tract and their pharmacological treatment. Anaesthesia & Intensive Care Medicine, 25(9), 623-629. https://doi.org/https://doi.org/10.1016/j.mpaic.2024.06.006
Fanda, R. B., Probandari, A., Yuniar, Y., Hendarwan, H., Trisnantoro, L., Jongeneel, N., & Kok, M. O. (2024). The availability of essential medicines in primary health centres in Indonesia: achievements and challenges across the archipelago. The Lancet Regional Health - Southeast Asia, 22, 100345. https://doi.org/https://doi.org/10.1016/j.lansea.2023.100345
Gach, M. W., Lazarus, G., Simadibrata, D. M., Sinto, R., Saharman, Y. R., Limato, R., Nelwan, E. J., van Doorn, H. R., Karuniawati, A., & Hamers, R. L. (2024). Antimicrobial resistance among common bacterial pathogens in Indonesia: a systematic review. The Lancet Regional Health - Southeast Asia, 26, 100414. https://doi.org/https://doi.org/10.1016/j.lansea.2024.100414
García-Cárdenas, V., & Hohmeier, K. C. (2022). Chapter 4 - Implementation science to guide pharmacy and health services research. In S. P. Desselle, V. García-Cárdenas, C. Anderson, P. Aslani, A. M. H. Chen, & T. F. Chen (Eds.), Contemporary Research Methods in Pharmacy and Health Services (pp. 49-56). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-323-91888-6.00046-6
Ghozali, M. T. (2024). Assessment of knowledge, perception, and readiness for telepharmacy-assisted pharmaceutical services among young pharmacists in rural Indonesia. Exploratory Research in Clinical and Social Pharmacy, 16, 100513. https://doi.org/https://doi.org/10.1016/j.rcsop.2024.100513
Hadi, U., Duerink, D. O., Lestari, E. S., Nagelkerke, N. J., Keuter, M., Huis in't Veld, D., Suwandojo, E., Rahardjo, E., van den Broek, P., & Gyssens, I. C. (2008). Audit of antibiotic prescribing in two governmental teaching hospitals in Indonesia. Clinical Microbiology and Infection, 14(7), 698-707. https://doi.org/https://doi.org/10.1111/j.1469-0691.2008.02014.x
Hasanuddin H, Ruslin, M., Al-Jamaei, A. A., Van Cann, E. M., Helder, M. N., Tajrin, A., & Forouzanfar, T. (2024). Contextualizing sociocultural beliefs about cleft, knowledge of the treatments, and factors associated with delay of treatment in Eastern Indonesia. Journal of Stomatology, Oral and Maxillofacial Surgery, 125(6), 101766. https://doi.org/10.1016/j.jormas.2024.101766
Herawati, F., Ananta, S. C., Parwitha, I. A. A., Ressandy, S. S., Rahmatin, N. L., Rachmadini, N. A., Tangalobo, V. A., Setiasih, Yulia, R., Hak, E., Woerdenbag, H. J., & Avanti, C. (2020). Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals. Health Policy OPEN, 1, 100002. https://doi.org/https://doi.org/10.1016/j.hpopen.2019.100002
Hidayat, B., Ramadani, R. V., Rudijanto, A., Soewondo, P., Suastika, K., & Siu Ng, J. Y. (2022). Direct Medical Cost of Type 2 Diabetes Mellitus and Its Associated Complications in Indonesia. Value in Health Regional Issues, 28, 82-89. https://doi.org/https://doi.org/10.1016/j.vhri.2021.04.006
Himawan, R. (2012). PHP39 Prescription Filling on Outpatient Health Care Departments: An Indonesia Family Life Survey (IFLS) Year 2007 – 2008 Based Study. Value in Health, 15(7), A616. https://doi.org/https://doi.org/10.1016/j.jval.2012.08.090
Jónsdóttir, F., Blöndal, A. B., Guðmundsson, A., Bates, I., Stevenson, J. M., & Sigurðsson, M. I. (2024). Potentially Inappropriate Medication Use and Polypharmacy Before and After Admission to Internal Medicine for Older Patients. The American Journal of Medicine. https://doi.org/https://doi.org/10.1016/j.amjmed.2024.07.026
Jormanainen, V., & Relander, T. (2019). Pdg104 Decreasing Number Of Prescriptions After They Became Mandatory And Their Validity Period Was Extended To Two Years: Case Finland Since 2017. Value in Health, 22, S614. https://doi.org/https://doi.org/10.1016/j.jval.2019.09.1117
Kosen, S. (2022). Coverage and implementation of healthcare delivery for cancer under national health insurance, experience of Indonesia. The Lancet Regional Health - Southeast Asia, 6, 100065. https://doi.org/https://doi.org/10.1016/j.lansea.2022.100065
Lakka, S. B., Maidin, A., Anggraeni, R., & Irwandy. (2020). Professional description of caregiver based on SNARS 1st edition in RSUD Makassar City. Enfermería Clínica, 30, 1-4. https://doi.org/https://doi.org/10.1016/j.enfcli.2020.06.002
Limato, R., Lazarus, G., Dernison, P., Mudia, M., Alamanda, M., Nelwan, E. J., Sinto, R., Karuniawati, A., Rogier van Doorn, H., & Hamers, R. L. (2022). Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention. The Lancet Regional Health - Southeast Asia, 2, 100013. https://doi.org/https://doi.org/10.1016/j.lansea.2022.05.002
McDonough, R. P., McDonough, A., & Doucette, W. R. (2022). Use of medication regimen complexity to target services in the community. Journal of the American Pharmacists Association, 62(3), 750-756. https://doi.org/https://doi.org/10.1016/j.japh.2021.12.011
Octavia, R., & Sari, S. (2024). Health related quality of life (HRQol) in chronic kidney failure patients at Arifin Ahmad Regional General Hospital Riau Province. Jurnal Ilmiah Farmako Bahari, 15(1), 72-83.
Pilmis, B., Rouzaud, C., To-Puzenat, D., Gigandon, A., Dauriat, G., Feuillet, S., Mitilian, D., Issard, J., Monnier, A. L., Lortholary, O., Fadel, E., & Le Pavec, J. (2024). Description, clinical impact and early outcome of S. maltophilia respiratory tract infections after lung transplantation, A retrospective observational study. Respiratory Medicine and Research, 86, 101130. https://doi.org/https://doi.org/10.1016/j.resmer.2024.101130
Prawiroharjo, P., Anggraini, H., Geraldi, I. P., Octaviana, F., Budikayanti, A., Safri, A. Y., Wiratman, W., Indrawati, L. A., Fadli, N., Harsono, A. R., & Hakim, M. (2024). Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application. Heliyon, 10(10), e30713. https://doi.org/https://doi.org/10.1016/j.heliyon.2024.e30713
Purwono, S., Nisa, U., Astana, P. R. W., Wijayaningsih, R. A., Wicaksono, A. J., Wahyuningsih, M. S. H., Kertia, N., Mustofa, M., Wahyuono, S., & Fakhrudin, N. (2023). Factors Affecting the Perception of Indonesian Medical Doctors on Herbal Medicine Prescription in Healthcare Facilities: Qualitative and Quantitative Studies. Journal of Herbal Medicine, 42, 100747. https://doi.org/https://doi.org/10.1016/j.hermed.2023.100747
Putri, A. E., Ma’wa, J., Habibie, & Bahar, M. A. (2024). Knowledge, attitudes, and practices of hospital pharmacists regarding clinically relevant drug interactions: A multi-center regional survey in Indonesia. Pharmacia, 71, 1-9. https://doi.org/https://doi.org/10.3897/pharmacia.71.e130998
Rahmadani, S., Marhani, Abadi, M. Y., Marzuki, D. S., Sudirman, & Fajrin, M. A. (2020). Analysis of independent National Health Insurance ownership of informal workers: Study of market traders in Gowa District, Indonesia. Enfermería Clínica, 30, 295-299. https://doi.org/https://doi.org/10.1016/j.enfcli.2020.06.076
Rahmawati, A. N., & Mutmainah, N. (2023). Evaluasi Peresepan Obat Berdasarkan Indikator World Health Organization (Who) Di Puskesmas Kecamatan Karanganyar. Usadha Journal of Pharmacy, 2(1), 133-143. https://doi.org/10.23917/ujp.v2i1.142
Raut, S., Mellor, R., Meurk, C., Lam, M., Lane, J., Khoo, A., Cronin, A., Smith, S., Heffernan, E., & Johnson, L. (2025). Prevalence and factors associated with polypharmacy in military and veteran populations: A systematic review and meta-analysis. Journal of Affective Disorders, 369, 411-420. https://doi.org/https://doi.org/10.1016/j.jad.2024.10.025
Stepanovic, B., Regli, A., Becke-Jakob, K., & von Ungern-Sternberg, B. S. (2024). Preoperative preparation of children with upper respiratory tract infection: a focussed narrative review. British Journal of Anaesthesia. https://doi.org/https://doi.org/10.1016/j.bja.2024.07.035
Yuniar, Y., Prayitno, L., Prihartini, N., & Herman, M. J. (2020). The implementation of pharmaceutical services standard in 43 hospitals in Indonesia. Enfermería Clínica, 30, 192-196. https://doi.org/https://doi.org/10.1016/j.enfcli.2020.06.043
Zairina, E., Dhamanti, I., Nurhaida, I., Mutia, D. S., & Natesan, A. (2024). Analysing of drug patterns in primary healthcare centers in Indonesia based on WHO's prescribing indicators. Clinical Epidemiology and Global Health, 30, 101815. https://doi.org/https://doi.org/10.1016/j.cegh.2024.101815
Zare, P., Poustchi, H., Mohammadi, Z., Mesgarpour, B., Akbari, M., Kamalipour, A., Abdipour-Mehrian, S. R., Hashemi, E.-S., Ghamar-Shooshtari, A., Hosseini, S. A., Malekzadeh, R., Bazrafshan Drissi, H., Malekzadeh, F., & Molavi Vardanjani, H. (2024). Polypharmacy and medication usage patterns in hypertensive patients: Findings from the Pars Cohort Study. Research in Social and Administrative Pharmacy, 20(11), 1038-1046. https://doi.org/https://doi.org/10.1016/j.sapharm.2024.07.006
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