Antibacterial activity of Sappan (Caesalpinia sappan L.) wood methanol extract against Staphylococcus epidermidis

Authors

  • Waro Atunnisa Universitas Muhammadiyah Banjarmasin
  • Irfan Zamzani Universitas Muhammadiyah Banjarmasin
  • Siti Nashihah Universitas Muhammadiyah Banjarmasin

DOI:

https://doi.org/10.12928/mf.v20i1.21900

Keywords:

Caesalpinia sappan L., Antibacterial, S. epidermidis, Ultrasound-Assisted Extraction (UAE)

Abstract

The entry and proliferation of microorganisms, such as bacteria, cause skin infections. One of the bacteria that causes skin infections is Staphylococcus epidermidis. Sappan (Caesalpinia sappan L.) wood has been known to have various pharmacology activities, one of which is antibacterial, so its activities need to be developed and improved. This study aimed to determine the activity of the methanol extract of Sappan (C. sappan L.) wood as an antibacterial against S. epidermidis. This research was conducted by extracting Sappan wood powder with 96% methanol as solvent using the Ultrasound-Assisted Extraction (UAE) method and testing for antibacterial activity with concentrations of 25%, 50%, 75% and 100% using the disc method. Results showed that the methanol extract of Sappan wood had an antibacterial activity; the highest inhibition zone at a concentration of 75% was 29.25 mm. Sappan wood was expected to be a promising alternative therapy for overcoming acne problems and can increase economic value for the wider community.

 

References

Amalia, A., Sari, I. & Nursanty, R. (2017) Aktivitas antibakteri ekstrak etil asetat daun sembung terhadap bakteri MRSA, Prosiding Seminar Nasional Botik, pp. 387–391.

Arista, Y. et al. (2013) Formulasi Dan Uji Aktivitas Gel Antijerawat Ekstrak Umbi Bakung (Crinum Asiaticum L.) Terhadap Bakteri Staphylococcus Aureus Secara in Vitro, PHARMACON Jurnal Ilmiah Farmasi – UNSRAT, 2(02), pp. 2302–2493.

Armaleni, A., Nasir, N. & Agustien, A. (2019) Antagonis Pseudomonas fluorescens indegenous terhadap Ralstonia solanacearum pada Tanaman Tomat (Lycopersicum esculentum), Metamorfosa: Journal of Biological Sciences, 6(1), p. 119. doi: 10.24843/metamorfosa.2019.v06.i01.p19.

Cahyaningtyas, D. M., Puspawati, N. & Binugraheni, R. (2019) Uji Aktivitas Antibakteri Ekstrak Etanolik Kayu Secang (Caesalpinia sappan L.) terhadap Staphylococcus aureus, Biomedika, 12(2), pp. 205–216. doi: 10.31001/biomedika.v12i2.614.

Dharmayanti, N. M. D. & Arjita, I. P. D. (2019) Uji Daya Hambat Ekstrak Batang Kayu Secang (Caesalpinia Sappan L.) Terhadap Bakteri Escherichia Coli, Jurnal Kedokteran, 4(1), p. 685. doi: 10.36679/kedokteran.v4i1.60.

Hamzah, A. (2019) Analisis In Vitro Aktivitas Antibakteri Daun Sisik Naga (Drymoglossum pilosellaoides) Terhadap Bakteri Vibrio harveyi dan Vibrio parahaemolyticus, Journal of Aquaculture and Fish Health, 8(2), p. 86. doi: 10.20473/jafh.v8i2.11984.

Kadri, M. F. ., Sunarni, T., Pamudji, G., & Zamzani, I. (2019). Aktivitas Antioksidan Ekstrak Etanol Daun Pelawan (Tristaniopsis obovate. Benn) Dengan Metode Penangkapan Radikal Bebas 2,2 - (Antioxidant Activity Of Ethanol Extract Of Pelawan Leaf (Tristaniopsis obovate . Benn). Journal of Current Pharmaceutical Science, 2(2), 167–172.

Kursia, S. et al. (2016) Uji Aktivitas Antibakteri Ekstrak Etilasetat Daun Sirih Hijau (Piper betle L.) terhadap Bakteri Staphylococcus epidermidis, Indonesian Journal of Pharmaceutical Science and Technology, 3(2), pp. 72–77.

Milah, N., Bintari, S. H. & Mustikaningtyas, D. (2016) Pengaruh Konsentrasi Antibakteri Propolis terhadap Pertumbuhan Bakteri Streptococcus pyogenes secara In Vitro, Life Science, 5(2), pp. 95–99.

Neswati, N. & Ismanto, S. D. (2018) Ekstraksi Komponen Bioaktif Serbuk Kayu Secang (Caesalpinia sappan L) Dengan Metode Ultrasonikasi, Jurnal Teknologi Pertanian Andalas, 22(2), p. 187. doi: 10.25077/jtpa.22.2.187-194.2018.

Retnaningsih, A., Primadiamanti, A. & Anisah, F. (2019) Uji Daya Hambat Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L.) GRIFF) Terhadap Bakteri Staphylococcus epidermidis dan Propionibacterium acnes Penyebab Jerawat Dengan Metode Cakram, Jurnal Analisis Farmasi, 4(1), pp. 1–9.

Rosidah, M. S., Lambui, O. & Suwastika, I. N. (2018) Ekstrak Daun Tumbuhan Macaranga tanarius ( L .) M . A Menghambat Laju Pertumbuhan Bakteri Staphylococcus epidermidis, Journal of Science and Technology 1, 7(1), pp. 64–70.

Suryana, S., Nuraeni, Y. Y. A. & Rostinawati, T. (2017) Aktivitas Antibakteri Ekstrak Etanol Dari Lima Tanaman Terhadap Bakteri Staphylococcus Epidermidis Dengan Metode Mikrodilusi M7 – A6CLSI, Indonesian Journal of Pharmaceutical Science and Technology, 4(1), p. 1. doi: 10.15416/ijpst.v4i1.8982.

Wijayati, N. et al. (2014) Transformasi α-Pinena dengan Bakteri Pseudomonas aeruginosa ATCC 25923, Biosaintifika: Journal of Biology & Biology Education, 6(1), pp. 24–28. doi: 10.15294/biosaintifika.v6i1.2931.

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Published

2023-03-16

Issue

Section

Pharmacology & Biology