FORMULASI TABLET SERBUK PISANG RAJA (Musa xparadisiaca AAB) SEBAGAI PENUTUP TUKAK LAMBUNG PADA TIKUS

Abstract

Mucoadhesive is a topic of current interest in the design of drug delivery system
and treatment of peptic ulcers. This concept is based on the strength of adhesion of a
protective material to the mucosa. King Banana (Musa xparadisiaca AAB) is often
used in the treatment of abdominal pain. It has been suspected having muchoadhesive
strength to cover peptic ulcer. The study was armed to formulate king banana tablet
which has muchoadhesive ability to protect gastric mucosa become ulcer. The aim of
peptic ulcer cover test was to see the ability of king banana tablet to covered ulcer at the
groups test that received different treatment of the negative control group (solvent), the
banana tablet suspension group, and sucralfate group. The ulcer severity was
determined by scoring method. All experimental data were tested by SPSS analytical
statistics. The result showed that king banana tablet has similar strength to peptic ulcer
cover of sucralfat and not significantly different.