PENGEMBANGAN SENYAWA TURUNAN BENZALASETON SEBAGAI SENYAWA TABIR SURYA
Abstract
The goal of this research was to synthesize benzalaceton derivative i.e. 4-dimethyl-aminodibenzalaceton
to increase the potency as sunscreen agent. The synthesis was carried out through aldol
condensation reaction with 4- dimetilamino-benzaldehida as a starting material and NaOH as catalyst
at various reaction times i.e. 3 , 4 and 6 hours. The characterizations of the product was observed by
melting point, FTIR and 1
H NMR spectrometers. The product was obtained as a yellowish orange
solid with a melting point between 62-640
C. The activity assay as sunscreen agent showed that the 4 –
dimethylamino-dibenzalaseton have a maximum wavelength at 340 nm, so its can be active as a
sunscreen in the UV - A rays. The SPF value at 15 ppm was 17.409 with ultra protection type.
Keywords
Full Text:
PDFDOI: http://dx.doi.org/10.12928/pharmaciana.v4i1.395
Refbacks
- There are currently no refbacks.
Copyright (c) 2021 Susy Yunita Prabawati, A Wijayanto, Aria Wirahadi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Office: Faculty of Pharmacy, Universitas Ahmad Dahlan
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia
Kode pos 55164
Email: pharmaciana@pharm.uad.ac.id