Determination of Sun Protection Factor and Antioxidant Properties of Cream Formulation of Kencur (Kaempferia galanga L) and Temu Kunci (Boesenbergia pandurata (Roxb.) Schlecht) Rhizomes Extract

Shintia Lintang Charisma, Wiranti Sri Rahayu, Retno Wahyuingrum

Abstract


Kencur (Kaempferia galanga, L.) rhizome contain ethyl-p-methoxycinnamate (EPMS) which has sunscreen properties. Temu kunci (Boesenbergia pandurata (Roxb) Schlecht) rhizome contains  flavonoid and essential oils with oxidant radical scavenging properties. The aims  of this study were  to obtain the optimum physical properties of sunscreen and antioxidant cream and to compare the sun protection factor (SPF) values and antioxidant activity of kencur and temu kunci rhizomes extract before and after formulated.

This research used Simplex Latice Design (SLD) model with 2 components of kencur extract and temu kunci extract. Based on the SLD model obtained optimum formula design, then the SPF values and antioxidant activity were studied by UV spectrophotometric method and DPPH method respectively.

Based on SLD model obtained optimum formula that containing kencur : temu kunci extract 80%:20% (formula A) and 70%:30% (formula B). The SPF values of  kencur extract, formula A and formula B were  4.505, 5.024 and 4.511 respectively. Antioxidant activity showed that the IC50 of formula A, formula B, temu kunci extract, BHT and Vitamin E were 109.15 µg/ml, 95.23 µg/ml, 10.20 µg/ml, 22.33 µg/ml and 8.78 µg/ml respectively.

Cream formula A and formula B have optimum physical properties. The SPF value of the optimum formulations were higher than SPF value of kencur extract. Antioxidant activity of that combinations were  lower than temu kunci extract, BHT and Vitamin E.


Keywords


Kencur, temu kunci, SPF, antioxidant, Simplex Lattice Design

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References


Cakhyo, Y.N., 2010, Pengaruh penambahan propilenglikol terhadap sifat fisik dan efektifitas gel tabir surya ekstrak kencur (Kaempferia galanga L.) dalam basis Na CMC [Skripsi], Purwokerto, Universitas Muhammadiyah Purwokerto.

Chahyadi A., Rika H., Komar R. and Elfahmi, 2014, Boesenbergia pandurata Roxb., An Indonesian Medicinal Plant: Phytochemistry, Biological Activity, Plant Biotechnology, Procedia Chemistry.

Ekowati J., Suko H., and Iwan S.H., 2016, Ethyl p-methoxycinnamate from Kaempferia galanga inhibits angiogenesis through tyrosine kinase, Universa Medicina, 34(1):43-51.

Gajardo S., Marilú A,, Tamara S., Felipe S., José L., Cristina Q., Pedro and Julio B., 2016, Determination of sun protection factor and antioxidant properties of six Chilean Altiplano plants, Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 15 (5): 352 – 363.

Nihlati A., I., Abdul R., dan Triana H., 2011, Daya Antioksidan Rimpang Temu Kunci [Boesenbergia pandurata (Roxb.) Schlecth] dengan Metode Penangkapan Radikal DPPH (1,1-difenil-2-pikrilhidrazil).

Nurhayati, E.S., 2011, Penggunaan Tween 80 dan Span 80 sebagai Emulgator dalam Formulasi Sediaan Krim M/A Tabir Surya Ekstrak Kencur (Kaempferia galanga, L) [Skripsi], Purwokerto, Universitas Muhammadiyah Purwokerto.

Sirisangtragul W. and Bungorn S., 2011, Effects of Kaempferia galanga L. and ethyl-p-methoxycinnamate (EPMC) on hepatic microsomal cytochrome P450s enzyme activities in mice, Songklanakarin Journal of Science andTechnology, 33 (4), 411-417.

Tewtrakul S, Supreeya Y.,, Sopa K. and Latthya A, 2005, Chemical components and biological activities of volatile oil of Kaempferia galanga Linn., Songklanakarin Journal of Science andTechnology, 27(Suppl. 2) : 503-507.




DOI: http://dx.doi.org/10.12928/pharmaciana.v8i2.11891

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