Sleep quality and duration during pandemic uninvolved to impaired fasting glucose and hyperuricemia among health care practitioners

Phebe Hendra, Fenty Fenty, Christianus Heru Setiawan, Leonardo Susanto Utomo, Gregorius Bhaskara Wikanendra, Putu Dyana Christasani, Dita Maria Virginia

Abstract


Sleep quality and sleep duration might be more disturbed throughout the pandemic of Covid-19 among health care practitioners (HCPs). It could influence impaired fasting glucose (IFG) and hyperuricemia. Therefore, the objective of this study was to assess the association between sleep with IFG and hyperuricemia among HCPs throughout the pandemic of Covid-19. We conducted a cross-sectional study that enrolled 58 HCPs in the tertiary hospital. Self-reported questionnaire related to their sleep quality and duration using the Pittsburg Sleep Quality Index (PSQI) were performed by participants. Fasting plasma glucose (FPG) and uric acid (UA) were examined after 10-12 hours of fasting to define IFG and hyperuricemia. A total of 58 HCPs detected 34.5% had IFG and 24.1% had hyperuricemia. We could not identify any statistically significant participants characteristic based on IFG. HCPs who shift workers were 21.4% hyperuricemia compared to 54.4 non-hyperuricemia (p=0.03). There were no different characteristics according to the quality and duration of sleep, where 72.4% HCPs had good quality and duration of sleep. However, we found that sleep medication used scores were higher in IFG group (0.30 ± 0.57) than non-IFG (0.03 ± 0.16) (p<0.01). This study could not detect a significant relationship between quality and/or duration of sleep, with IFG and hyperuricemia. Shift worker significant associated with hyperuricemia (p<0.05). The association between quality and duration of sleep with IFG and hyperuricemia was not found among HCPs, especially during the Covid-19 pandemic. An alert where the IFG group had high sleep medication used scores, and shift workers had a lower risk of hyperuricemia.


Keywords


sleep quality; sleep duration; impaired fasting glucose; hyperuricemia; health care practitioners; Covid-19

Full Text:

PDF

References


Abbas, A., Al-Otaibi, T., Gheith, O. A., Nagib, A. M., Farid, M. M., & Walaa, M. (2021). Sleep quality among healthcare workers during the covid-19 pandemic and its impact on medical errors: Kuwait experience. Turkish Thoracic Journal, 22(2), 142–148. https://doi.org/10.5152/TurkThoracJ.2021.20245

Alnofaiey, Y. H., Alshehri, H. A., Alosaimi, M. M., Alswat, S. H., Alswat, R. H., Alhulayfi, R. M., … Alsubaie, R. M. (2020). Sleep disturbances among physicians during COVID-19 pandemic. BMC Research Notes, 13(1), 493. https://doi.org/10.1186/s13104-020-05341-6

American Diabetes Association. (2020). Standards of Medical Care in Diabetes. The Journal of Clinical and Applied Research and Education, 43(1), 1–212. Retrieved from https://care.diabetesjournals.org/content/diacare/suppl/2019/12/20/43.Supplement_1.DC1/Standards_of_Care_2020.pdf

Billiet, L., Doaty, S., Katz, J. D., & Velasquez, M. T. (2014). Review of Hyperuricemia as New Marker for Metabolic Syndrome. ISRN Rheumatology, 2014, 852954. https://doi.org/10.1155/2014/852954

Bin, Y. S. (2016). Is sleep quality more important than sleep duration for public health? Sleep. 39(9), 1629-1630. https://doi.org/10.5665/sleep.6078

Binh, T. Q., Tran Phuong, P., Thanh Chung, N., Nhung, B. T., Tung, D. D., Quang Thuyen, T., … Danh Tuyen, L. (2019). First Report on Association of Hyperuricemia with Type 2 Diabetes in a Vietnamese Population. International Journal of Endocrinology, 2019. https://doi.org/10.1155/2019/5275071

Briançon-Marjollet, A., Weiszenstein, M., Henri, M., Thomas, A., Godin-Ribuot, D., & Polak, J. (2015). The impact of sleep disorders on glucose metabolism: Endocrine and molecular mechanisms. Diabetology and Metabolic Syndrome. 7, 25. https://doi.org/10.1186/s13098-015-0018-3

Buxton, O. M., Pavlova, M., Reid, E. W., Wang, W., Simonson, D. C., & Adler, G. K. (2010). Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 59(9), 2126–2133. https://doi.org/10.2337/db09-0699

Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989). The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2), 193–213. https://doi.org/10.1016/0165-1781(89)90047-4

Chattu, V., Chattu, S., Burman, D., Spence, D., & Pandi-Perumal, S. (2019). The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus. Healthcare, 7(1), 37. https://doi.org/10.3390/healthcare7010037

Chou, Y. T., Li, C. H., Shen, W. C., Yang, Y. C., Lu, F. H., Wu, J. S., & Chang, C. J. (2020). Association of sleep quality and sleep duration with serum uric acid levels in adults. PLoS ONE, 15(9 September 2020), e0239185. https://doi.org/10.1371/journal.pone.0239185

Ferini-Strambi, L., Zucconi, M., Casoni, F., & Salsone, M. (2020, October 1). COVID-19 and Sleep in Medical Staff: Reflections, Clinical Evidences, and Perspectives. Current Treatment Options in Neurology. 22(10), 29. https://doi.org/10.1007/s11940-020-00642-4

Gupta, B., Sharma, V., Kumar, N., & Mahajan, A. (2020). Anxiety and sleep disturbances among health care workers during the covid-19 pandemic in India: Cross-sectional online survey. JMIR Public Health and Surveillance, 6(4), e24206. https://doi.org/10.2196/24206

Hung, H. C., Yang, Y. C., Ou, H. Y., Wu, J. S., Lu, F. H., & Chang, C. J. (2013). The relationship between impaired fasting glucose and self-reported sleep quality in a Chinese population. Clinical Endocrinology, 78(4), 518–524. https://doi.org/10.1111/j.1365-2265.2012.04423.x

Irwin, M. R., Olmstead, R., & Carroll, J. E. (2016). Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation. Biological Psychiatry, 80(1), 40–52. https://doi.org/10.1016/j.biopsych.2015.05.014

Kalsbeek, A., La Fleur, S., & Fliers, E. (2014). Circadian control of glucose metabolism. Molecular Metabolism, 3(4), 372-383. https://doi.org/10.1016/j.molmet.2014.03.002

Khandelwal, D., Dutta, D., Chittawar, S., & Kalra, S. (2017). Sleep disorders in type 2 diabetes. Indian Journal of Endocrinology and Metabolism, 21(5), 758-761. https://doi.org/10.4103/ijem.IJEM_156_17

Kim, C. E., Shin, S., Lee, H.-W., Lim, J., Lee, J., Shin, A., & Kang, D. (2018). Association between sleep duration and metabolic syndrome: a cross-sectional study. BMC Public Health, 18(1), 720. https://doi.org/10.1186/s12889-018-5557-8

Kim, S.-W., Jang, E.-C., Kwon, S.-C., Han, W., Kang, M.-S., Nam, Y.-H., & Lee, Y.-J. (2016). Night shift work and inflammatory markers in male workers aged 20–39 in a display manufacturing company. Annals of Occupational and Environmental Medicine, 28(1), 1–9. https://doi.org/10.1186/s40557-016-0135-y

Kocevska, D., Blanken, T. F., Van Someren, E. J. W., & Rösler, L. (2020). Sleep quality during the COVID-19 pandemic: not one size fits all. Sleep Medicine, 76, 86–88. https://doi.org/10.1016/j.sleep.2020.09.029

Kothari, V., Cardona, Z., Chirakalwasan, N., Anothaisintawee, T., & Reutrakul, S. (2021). Sleep interventions and glucose metabolism: systematic review and meta-analysis. Sleep Medicine. 78, 24-35. https://doi.org/10.1016/j.sleep.2020.11.035

Krupa, S., Paramedic, D. F., Mędrzycka-Dąbrowska, W., Lewandowska, K., Witt, P., & Ozga, D. (2021). Sleep disorders among Nurses and other Health Care workers in Poland during the COVID-19 pandemic. Applied Nursing Research, 59, 151412. https://doi.org/10.1016/j.apnr.2021.151412

Kushiyama, A., Nakatsu, Y., Matsunaga, Y., Yamamotoya, T., Mori, K., Ueda, K., … Asano, T. (2016). Role of uric acid metabolism-related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis. Mediators of Inflammation, 2016, 8603164. https://doi.org/10.1155/2016/8603164

Lyngdoh, T., Marques-Vidal, P., Paccaud, F., Preisig, M., Waeber, G., Bochud, M., & Vollenweider, P. (2011). Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based colaus study. PLoS ONE, 6(5), e19901. https://doi.org/10.1371/journal.pone.0019901

Mollayeva, T., Thurairajah, P., Burton, K., Mollayeva, S., Shapiro, C. M., & Colantonio, A. (2016). The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep Medicine Reviews, 25, 52-73. https://doi.org/10.1016/j.smrv.2015.01.009

Morisky, D. E., Ang, A., Krousel-Wood, M., & Ward, H. J. (2008). Predictive validity of a medication adherence measure in an outpatient setting. Journal of Clinical Hypertension, 10(5), 348–354. https://doi.org/10.1111/j.1751-7176.2008.07572.x

Oh, J. S., Choi, W. J., Lee, M. K., Han, S. W., Song, S. H., Yun, J. W., & Han, S. H. (2014). The association between shift work and hyperuricemia in steelmaking male workers. Annals of Occupational and Environmental Medicine, 26(1), 42. https://doi.org/10.1186/s40557-014-0042-z

Ohayon, M. M. (2011). Epidemiological Overview of sleep Disorders in the General Population. Sleep Medicine Research, 2(1), 5. https://doi.org/10.17241/smr.2011.2.1.1

Pagel, J. F., Pandi-Perumal, S. R., & Monti, J. M. (2018). Treating insomnia with medications. Sleep Science and Practice, 2(5), 1–12. https://doi.org/10.1186/s41606-018-0025-z

Papandreou, C., Babio, N., Díaz-López, A., Martínez-González, M., Becerra-Tomas, N., Corella, D., … Salas-Salvadó, J. (2019). Sleep duration is inversely associated with serum uric acid concentrations and uric acid to creatinine ratio in an elderly mediterranean population at high cardiovascular risk. Nutrients, 11(4), 761. https://doi.org/10.3390/nu11040761

Proctor, A., & Bianchi, M. T. (2012). Clinical Pharmacology in Sleep Medicine. ISRN Pharmacology, 2012, 914168. https://doi.org/10.5402/2012/914168

Qin, Y., Lou, P., Chen, P., Zhang, L., Zhang, P., Chang, G., … Qiao, C. (2016). Interaction of poor sleep quality, family history of type 2 diabetes, and abdominal obesity on impaired fasting glucose: A population-based cross-sectional survey in China. International Journal of Diabetes in Developing Countries, 36(3), 277–282. https://doi.org/10.1007/s13410-015-0410-4

Roddy, E., Muller, S., Hayward, R., & Mallen, C. D. (2013). The association of gout with sleep disorders: A cross-sectional study in primary care. BMC Musculoskeletal Disorders, 14(1), 119. https://doi.org/10.1186/1471-2474-14-119

Schmidt, R. E., Cullati, S., Mostofsky, E., Haller, G., Agoritsas, T., Mittleman, M. A., … Courvoisier, D. S. (2015). Healthcare-Related Regret among Nurses and Physicians Is Associated with Self-Rated Insomnia Severity: A Cross-Sectional Study. PLoS One, 10(10), e0139770. https://doi.org/10.1371/journal.pone.0139770

Shreffler, J., Petrey, J., & Huecker, M. (2020). The impact of COVID-19 on healthcare worker wellness: A scoping review. Western Journal of Emergency Medicine, 21(5), 1059–1066. https://doi.org/10.5811/westjem.2020.7.48684

Tovchiga, O. V., & Shtrygol’, S. Y. (2014). Uric acid and central nervous system functioning (a literature review). Biology Bulletin Reviews, 4(3), 210–221. https://doi.org/10.1134/s2079086414030086

Tsalamandris, S., Antonopoulos, A. S., Oikonomou, E., Papamikroulis, G. A., Vogiatzi, G., Papaioannou, S., … Tousoulis, D. (2019). The role of inflammation in diabetes: Current concepts and future perspectives. European Cardiology Review, 14(1), 50-59. https://doi.org/10.15420/ecr.2018.33.1

Woyesa, S. B., Hirigo, A. T., & Wube, T. B. (2017). Hyperuricemia and metabolic syndrome in type 2 diabetes mellitus patients at Hawassa university comprehensive specialized hospital, South West Ethiopia. BMC Endocrine Disorders, 17(1), 76. https://doi.org/10.1186/s12902-017-0226-y

Zhang, J., Ma, R. C. W., Kong, A. P. S., So, W. Y., Li, A. M., Lam, S. P., … Wing, Y. K. (2011). Relationship of sleep quantity and quality with 24-hour urinary catecholamines and salivary awakening cortisol in healthy middle-aged adults. Sleep, 34(2), 225–233. https://doi.org/10.1093/sleep/34.2.225

Zhou, Y., Ding, H., Zhang, Y., Zhang, B., Guo, Y., Cheung, T., … Tang, Y. (2021). Prevalence of poor psychiatric status and sleep quality among frontline healthcare workers during and after the COVID-19 outbreak: a longitudinal study. Translational Psychiatry, 11(1), 223. https://doi.org/10.1038/s41398-020-01190-w

Zhou, Y., Zhao, M., Pu, Z., Xu, G., & Li, X. (2018). Relationship between oxidative stress and inflammation in hyperuricemia Analysis based on asymptomatic young patients with primary hyperuricemia. Medicine, 97(49), e13108. https://doi.org/10.1097/MD.0000000000013108

Zhu, B. Q., Li, X. M., Wang, D., & Yu, X. F. (2014). Sleep quality and its impact on glycaemic control in patients with type 2 diabetes mellitus. International Journal of Nursing Sciences, 1(3), 260–265. https://doi.org/10.1016/j.ijnss.2014.05.020




DOI: http://dx.doi.org/10.12928/pharmaciana.v12i2.20998

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Phebe Hendra, Fenty Fenty, Christianus Heru Setiawan, Leonardo Susanto Utomo, Gregorius Bhaskara Wikanendra, Putu Dyana Christasani, Dita Maria Virginia

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.


 
Pharmaciana
ISSN Print: 2088-4559 | ISSN Online: 2477-0256
Website: http://journal.uad.ac.id/index.php/PHARMACIANA
Office: Faculty of  Pharmacy, Universitas Ahmad Dahlan
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia
Kode pos 55164
Email: pharmaciana@pharm.uad.ac.id