A study of hemodynamic medicine use in intensive cardiac care unit of dr. Soedarso regional public hospital, Pontianak

Shoma Rizkifani, Intan Khairunnisa, Eka Kartika Untari

Abstract


Hemodynamic medicines are important to recover patients with a critical period in the ICCU. Hemodynamic medicines have a small range of dose so that it has a large effect on the therapy. Therefore, a study on the use of hemodynamic medicines and doses is necessarily conducted. This study aims to investigate the use and doses of hemodynamic medicines administered to patients in the ICCU of dr. Soedarso Hospital Pontianak. This study is observational research with a descriptive cross-sectional design. The research sample was 49 patients who had met the inclusion criteria. The data were analyzed descriptively to describe the frequency and percentage. The results show that a single hemodynamic medicine is administered to 65% of the patients and a combination of hemodynamic medicines is administered to 35% of the patients. The single medicine refers to dobutamine administered to 84.4% of the patients. Meanwhile, the combination of hemodynamic medicines consists of dobutamine and norepinephrine that are administered to 52.9% of the patients. The doses of hemodynamic medicines frequently administered to patients are 3-5 μg/kg/min dobutamine, 3-10 μg/kg/min dopamine, 0.01-2-2 μg/kg/min norepinephrine, and 1 mg/ml epinephrine. This study concludes that dobutamine (inotropic) is the most frequently used single hemodynamic medicine, and norepinephrine (vasopressor) is the most frequently used combined hemodynamic medicine for the ICCU patients at dr. Soedarso Regional Public Hospital, Pontianak.


Keywords


Dobutamine; ICCU; Hemodynamic agents; Norephinephrine

Full Text:

PDF

References


Aberg, J., Alvarez W, L, A., K, B., Baughman V, & J, B. (2009). Drug Information Handbook, 17th edition. Lexi-Comp for the American Pharmacists Association.

Amado, J., Gago, P., Santos, W., Mimoso, J., & de Jesus, I. (2016). Choque cardiogénico – fármacos inotrópicos e vasopressores. Revista Portuguesa de Cardiologia, 35(12), 681–695. https://doi.org/10.1016/j.repc.2016.08.004

Bistola, V., & Chioncel, O. (2017). Inotropes in acute heart failure. Continuing Cardiology Education, 3(3), 107–116. https://doi.org/10.1002/cce2.59

Casu, G., & Merella, P. (2015). Diuretic Therapy in Heart Failure - Current Approaches. European Cardiology Review, 10(1), 42. https://doi.org/10.15420/ecr.2015.10.01.42

Droogh, J. M., Smit, M., Absalom, A. R., Ligtenberg, J. J., & Zijlstra, J. G. (2015). Transferring the critically ill patient: are we there yet? Critical Care, 19(1), 62. https://doi.org/10.1186/s13054-015-0749-4

Firdaus, I., Lilihata, G., Kristianto, A., Simanjuntak, C. K., S., S., Danny, Irmalita, Dharma, S., Juzar, D. A., & Tobing, D. P. L. (2017). Hemodynamic profiles as a predistor of mortality and length of stay in ICCU: Insight from registry of acute and intensive cardiovascular care outcome. Indonesian Journal of Cardiology, 38, 160-167.

Herdiyanti, S. N., Kesoema, T. A., & Ningrum, F. H. (2018). Pengaruh deep breathing akut terhadap saturasi oksigen dan frekuensi pernapasan anak obsitas usia 7-12 tahun. Jurnal Kedokteran Diponegoro, 7(2), 1211-1221.

Huygh, J., Peeters, Y., Bernards, J., & Malbrain, M. L. N. G. (2016). Hemodynamic monitoring in the critically ill: an overview of current cardiac output monitoring methods. F1000Research, 5, 2855. https://doi.org/10.12688/f1000research.8991.1

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2014). 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults. JAMA, 311(5), 507. https://doi.org/10.1001/jama.2013.284427

Jentzer, J. C., Coons, J. C., Link, C. B., & Schmidhofer, M. (2015). Pharmacotherapy Update on the Use of Vasopressors and Inotropes in the Intensive Care Unit. Journal of Cardiovascular Pharmacology and Therapeutics, 20(3), 249-260. https://doi.org/10.1177/1074248414559838

Kasaoka, S. (2017). Evolved role of the cardiovascular intensive care unit (CICU). Journal of Intensive Care, 5(1), 72. https://doi.org/10.1186/s40560-017-0271-7

Levy, B., Perez, P., Perny, J., Thivilier, C., & Gerard, A. (2011). Comparison of norepinephrine-dobutamine to epinephrine for hemodynamics, lactate metabolism, and organ function variables in cardiogenic shock. A prospective, randomized pilot study. Critical Care Medicine, 39(3), 450-455. https://doi.org/10.1097/CCM.0b013e3181ffe0eb

Manolopoulos, P. P., Boutsikos, I., Boutsikos, P., Iacovidou, N., & Ekmektzoglou, K. (2020). Current use and advances in vasopressors and inotropes support in shock. Journal of Emergency and Critical Care Medicine, 4, 20-20. https://doi.org/10.21037/jeccm.2019.12.03

Nadia, P., Pramantara, I. D., & Ikawati, Z. (2015). Faktor-Faktor yang Mempengaruhi Kualitas Hidup Pasien Gagal Jantung Kronik. Jurnal Manajemen Dan Pelayanan Farmasi, 5(4), 259-266.

Nirmalasari, N. (2017). Deep Breathing Exercise and Active Range of Motion Efektif Menurunkan Dypsnea pada Pasien Congestive Heart Failure. NurseLine Journal, 2(2), 159-165.

Pollard, S., Edwin, S. B., & Alaniz, C. (2015). Vasopressor and Inotropic Management of Patients with Septic Shock. P&T, 40(7), 438-450.

Pudiarifanti, N., Pramantara, I. D., & Ikawati, Z. (2015). Faktor-Faktor yang mempengaruhi kualitas hidup pasien gagal jantung kronik. Jurnal Manajemen Dan Pelayanan Farmasi, 5(4), 259-266.

Riskesdas. (2018). Hasil Utama Riskesdas 2018. Kementerian Kesehatan Badan Penelitian dan Pengembangan Kesehatan.

Shafia, S., Chandluri, P., Ganpisetti, R., Lakshmi, D. B. V. S., & Swami5, D. P. A. (2016). Dobutamin Use in Cardiac Patients. World Journal of Pharmaceut World Journal of Pharmaceutical and Medical Research. World Journal of Pharmaceut World Journal of Pharmaceutical and Medical Research, 2(6), 1-8.

TW, S. (2015). Hemodynamics. HHS Public Access. Compr Physiol, 6(2), 975-1003.

Vollman, K. M. (2013). Understanding critically Ill patients hemodynamic response to mobilization. Critical Care Nursing Quarterly, 36(1), 17-27. https://doi.org/10.1097/CNQ.0b013e3182750767




DOI: http://dx.doi.org/10.12928/mf.v19i1.21538

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Shoma Rizkifani

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Media Farmasi
p-ISSN 1412-7946 | e-ISSN 2503-5223
Published by Universitas Ahmad Dahlan Yogyakarta Indonesia
Website: http://journal.uad.ac.id/index.php/Media-Farmasi/index
Email: mediafarmasi@pharm.uad.ac.id

Lisensi Creative Commons

This work is licensed under a Creative Commons Attribution 4.0 International License


View Media Farmasi Stats